When asked by her editor to investigate Sebastian Shaw and the Hellfire Club, Irene gets drawn into a conspiracy to kill Cable.

[volume & issue needed] Working for Cable, she also is a witness to many incredible events and lands a job as a reporter for the Daily Bugle by writing about them.

[volume & issue needed] She thinks Cable's power is getting to his head and calls him on it, even bringing a gun to her office to protect herself from him, should he go insane.

[volume & issue needed] When Cable secretly uses a virus to turn everybody on Earth pink, only to publicly restore them later to normal, he is lauded as a hero.

[volume & issue needed] Irene even learns to put up with Deadpool, Cable's new associate, who often expresses a romantic interest in her.

[5] Cable's evil clone Stryfe later forces Deadpool to murder Irene when he threatens the lives of Wade's family.