A significant scarp that can reach 800 meters in height and is the eastern portion of the Great Rift Valley surrounds the area on all sides.

Iringa is hence situated in Tanzania's southern highlands, bordering Mbeya, Njombe, Morogoro, Dodoma, and Singida areas.

The midland zone, in the central part of the region, lies at a height of 1,200–1,600 m (3,900–5,200 ft) above sea level and faces between 600–1,000 mm (24–39 in) of rain every year.

[10] The region is host to the Ruaha National Park, famous for its large herd of elephants and over 400 species of birds.

Pangwa, Chaga, Nyakyusa and Ngoni can be found in urban areas primarily engaged in business in the region.

In the 2015 general election, six candidates from the ruling Chama Cha Mapinduzi and one from CHADEMA won their respective seats.

[13] William Lukuvi, the MP for Ismani is the Cabinet Minister for Lands, Housing and Human Settlements Development.

On a per-capita basis, Iringa's 2012 figure of about TSh 1,400,000 ranks it second only to Dar es Salaam Region which includes the capital of Tanzania.

There is also carpentry and oil processing which comprise the bulk of industrial units found within the Iringa Region.