Her first attempt at success in the music industry came in 1995, when she joined singers-cum-rapper DJs Ragga Dee and Molar-Messe, as the group Da Hommies, and "Joss Jjew" Mawejje as a studio arranger/keyboardist,[2] assisting in the release of a series of singles including "Bamusakata", "Mukwano", and "Mukyala tokaba" in early 1995.

[4] In 1999, she joined Kanyomozi, her former schoolmate at Namasagali College, to form the R&B all-girl group called I-Jay.

[6] Since 2006, Namubiru released the songs "Y'ono", "Lwaki", "Bonna Obasinga", "Begombeko", "Birowoozo", for which she has received various awards in the Ugandan music industry.

[8][9][10] Namubiru has been widely criticised by her detractors for dressing "inappropriately" in her music videos and, at times, her concerts.

According to her critics, her costumes oppose traditional Ugandan dressing customs and set a bad example for other aspiring musicians.

However, many of her fans have defended her "creative" attire and perceive the accusations to be socially regressive and resistant to new styles.

On 24 November 2018 she survived an accident in Lake Victoria, where a cruise boat carrying party revellers capsized, killing 33 people.