The district headquarters at Luweero are approximately 75 kilometres (47 mi), by road, north of Kampala, Uganda's capital and largest city.

[2] Luweero District was the site of a fierce insurgency by the rebel group National Resistance Army and a brutal counter-insurgency by the government of Milton Obote, known as the Luweero War or the "Bush War", that left many thousands of civilians dead during the early to mid-1980s.

The area affected by the war has come to be known as the Luweero Triangle.

It has been estimated that 85 percent of the district population are engaged in agriculture.

[5] The following additional points of interest are located in Luweero District: