Isaac Asimov Presents The Great SF Stories 22 (1960) is an American science fiction anthology, the twenty-second volume in the Isaac Asimov Presents The Great SF Stories series, edited by Isaac Asimov and Martin H. Greenberg, which attempts to list the great science fiction stories from the Golden Age of Science Fiction.

They date the Golden Age as beginning in 1939 and lasting until 1963.

This volume was originally published by DAW books in February 1991.

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