[2] Osei serves as the chairman of Ghana Ports and Harbours Authority, Algebra Securities Ltd, Algebra Capital Ltd, and Intravenous Infusions Ltd.[3][4] Isaac Osei was born on March 29, 1951, at Ashanti Newtown in the Ashanti Region, Kumasi.
Osei, in addition, holds a master's degree in Development Economics, from Williams College in Massachusetts, USA from 1976 to 1977.
He was previously the Managing director of Tema oil Refinery and the Chief Executive Officer of Ghana CoCoa Board.
Whiles in London, he was elected to the position of chairperson at the board of governors of the Commonwealth Secretariat, UK.
He served as the managing director of Intravenous Infusions Limited, prior to his appointment as High commissioner of Ghana to the United Kingdom and Ambassador to Ireland by John.A.
He came third after Alan John Kyeremanten, while the President of Ghana Nana Akufo-Addo was elected as flagbearer of the New Patriotic Party.