Isabel Wood Holt (1899–1996) was the wife of former Governor of West Virginia Homer A. Holt and served as that state's First Lady, 1937-1941.
After leaving office, the Holts remained in Charleston, West Virginia, where the former governor practiced law.
Following his death in 1975, Isabel remained in Charleston in her home on Bridge Road.
She kept a garden on the place and grew the World's best tomatoes and canteloupes according to her grandson, Claiborne Holt Coyle.
Isabel Wood Holt died on September 5, 1996, and was buried in Lewisburg, West Virginia.