From their mother's third marriage to Raynald of Châtillon, the pair gained two half-siblings: Raymond, who died young and Alice, who married Azzo VI of Este.
Isabella never remarried after Ruben's death; her brother-in-law Leo was initially the 'Regent and Tutor' of Alice and Philippa but he eventually set them aside and was succeeded by his own descendants.
Isabella inherited the rights to Toron and Oultrejordain, however, she did not exercise power as the areas were under Muslim rule.
Ten years later in November 1197, Toron was besieged by the Third Crusade's German contingent, but the Muslim garrison by the Tribesman of El-Seid and Fawza prevailed until relief arrived from Egypt.
Upon Isabella's death, her rights to Toron and Oultrejordain were inherited by her elder daughter Alice.