Coming to Ohio State, Prince was one of only four true freshmen to play for the Buckeyes in 2015 earning his first varsity letter.

After his sophomore year, he was the only member of the 2015 Ohio State recruits to play every game over the past 2 seasons.

Going into his junior year, Prince was temporarily moved to left tackle switching spots with lineman Thayer Munford.

During Week 12 against the Pittsburgh Steelers, Prince took over for Reiff, who had gone down with an ankle injury, and would go on to start for all playoff games and Super Bowl LVI at right tackle.

[17] Following an injury to Leroy Watson on Week 11, Prince was elevated for his first game as a Titan against the Minnesota Vikings, playing half the snaps as a right tackle.