Iset Ta-Hemdjert or Isis Ta-Hemdjert, simply called Isis in her tomb, was an ancient Egyptian queen of the Twentieth Dynasty; the Great Royal Wife of Ramesses III and the Royal Mother of Ramesses VI.

[2] Ramesses IV was once thought to be this queen's own son too until it was revealed in a recent 2010 Journal of Egyptian Archaeology article that Queen Tyti was most likely to be this king's mother from copies of fragments of the tomb robbery papyri that Anthony Harris made revealing that she was Ramesses III's own wife plus the fact that she is known to have been a king's mother.

The corridor is decorated with scenes showing the queen before a variety of divinities including Ptah-Sokar, Atum and Osiris.

[5] The side rooms are decorated with scenes showing a variety of goddesses including Neith, Serket, Isis, and Nephthys.

[5] Fragments of a red granite sarcophagus were recovered during the excavations by Schiaparelli and are now in the Museo Egizio in Turin, Italy.