[1][2] There have been numerous accounts of human rights abuses against prisoners there.

[3][4][5] The Iranian intelligence community and Investigation police have their own wards.

[1] In 2013, six prisoners attempted to escape via a hand dug tunnel measuring 23 meters.

[8] In 2020, the United States placed sanctions on Isfahan Central Prison, alongside Zahedan Prison, due to alleged human rights abuses of "responsible for extrajudicial killings and arbitrary detention", and that Isfahan held more prisoners than it had the capacity to.

[11] Since September 2022, when the death of Mahsa Amini incited protests across the country, the prison has served both as a holding place for arrested protesters and as a site of protest against the execution of prisoners.