Isla Mitlán, is an island in the Gulf of California, located within Bahía de los Ángeles east of the Baja California Peninsula.

It is adjacent to the west coast of Isla Coronado.The island is uninhabited and is part of the Ensenada Municipality.

Isla Mitlán has two species of reptile, including Sauromalus hispidus (Spiny Chuckwalla) and Uta stansburiana (Common Side-blotched Lizard).

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