Isocoma hartwegii is a Mexican plant species in the family Asteraceae.

It has been found in the states of Jalisco, Zacatecas, Aguascalientes, Hidalgo, Guanajuato, and San Luis Potosí.

[4] Isocoma hartwegii is a subshrub.

Each flower head has 13-22 disc flowers but no ray flowers.

[4]