Isocrania is an extinct genus of brachiopods found during the Upper Cretaceous.

Early representatives were attached to the underground, but later species are presumed to be free living at an increasingly earlier age.

This was probably an adaptation to the increasing very thick and fine sedimentation during the latest Cretaceous.

Isocrania is round to ovate, up to 1 cm in diameter, and has 15-65 strong ribs, that start at ±½mm from the origin of growth (or umbo).

The attachment area is smaller than usual, and virtually absent in adults of later species.