Isola Sacra (the Holy Isle) is situated in the Lazio region of Italy south of Rome, near the Tyrrhenian Sea.

[3] The inhabitants of Portus were middle-class administrators, traders, merchants, and sea workers often descended from slaves.

The Isola Sacra Necropolis grew up alongside the road, which was discovered between the 1920s and the 1940s, while the land was being reclaimed.

Some of the necropolis buildings have two storeys, elaborately decorated with paintings, stucco work and mosaics.

The study of human skeletal remains from the site continues to provide important information about diet and morbidity in ancient Rome.