That's part of being an artist.In an interview with NPR, Kali Uchis spoke on the details of her relationship with her family and growing up alongside the lyrics of "Killer", stating: In that era of my life, I was still really young and I was just kind of figuring everything out.

Uchis supported the album with her 23-date North American "In Your Dreams" tour which commenced on September 13, 2018, in Seattle and ended on November 10, 2018, in Los Angeles.

[13][14] Uchis made her television debut on The Tonight Show alongside Tyler, the Creator to perform "After the Storm".

[16] Ilana Kaplan of The Independent wrote that Uchis "has been largely underrated the past few years, but Isolation might just finally give her the attention she deserves".

"[3] Q critic Rupert Howe praised Uchis' "natural pop charisma and ... ability to glide effortlessly between genres".

[22] For Rolling Stone, Joe Levy praised the album as "fascinating" and simultaneously "vintage and futuristic", comparing it to the works of Beck and Outkast.

[2] In a five-star review Thomas Smith of NME commented that "miraculously, [the album] feels in no way forced: it's a joy to witness her glide into any genre and totally own it".

[4] Pitchfork also included the album at number 38 on its list of 50 best albums of 2018, with Daphne Carr writing that it "pays tribute to pop's past while making it sound new through glowing homage to black and Latinx jukebox favorites and a global roster of collaborations housed in classic soul/R&B aesthetics.