Isomescaline (2,3,4-trimethoxyphenethylamine) is a lesser-known compound based on a well-known psychedelic drug.

Isomescaline was first synthesized by Alexander Shulgin.

In his book PIHKAL, it is suggested that any potentially active dose would be "greater than 400 mg".

[1] Despite its structural similarity to mescaline, isomescaline has produced no effects in humans.

Very little data exists about the pharmacological properties, metabolism, and toxicity of isomescaline.