[2] In 1907 he competed against Nicolae Titulescu for an open faculty position at the Law School of the University of Iași, and was successful in securing the appointment.

[8] Although he had previously praised Micescu as being "an eminent jurist," Nicolae Iorga was not pleased with the result: "Our Constitution should be the product of the nation, relying on strict principles of the soul and the manifestations of our people.

Our first Constitution was created by a certain Alecu Constantinescu, and that of last February by Istrate Micescu, an idiotic jurist who only sees that which is written in his manuals and that which the king has told him.

[2] According to some accounts, King Michael I offered safe passage to the West on his personal plane so that Micescu could set up a government-in-exile, but he refused.

He was re-arrested in March 1948 and held at Jilava Prison on charges that he and Nichifor Robu [ro] had set an organization (Salvarea Neamului) to overthrow the communist regime.

He was tried by the Bucharest Military Tribunal, presided by Colonel Mihail Vasilescu;[10] on 1 July 1948 he was sentenced to 20 years of forced labour for conspiracy and rebellion.

[12] Micescu lived in an imposing mansion at the entrance to the Cișmigiu Gardens in Bucharest; the property, located at 12, Ioan Zalomit Street, featured the largest private library in the city.

The plans were drawn by architect Edmond van Saanen Algi and the building contractor was the well-known engineer C. Corani.

Istrate Micescu would invite at his property his friends, including the writers Liviu Rebreanu, Ion Minulescu, Lucian Blaga, and Octavian Goga.