All proceeds from sales of the single were donated to Barack Obama's campaign of the same name, raising awareness of and fighting against sexual assault on college campuses in the United States.

The It's On Us campaign was launched by Barack Obama and the White House Council on Women and Girls on September 19, 2014, aiming to raise awareness about sexual assault on college campuses and encourage the public to recognize and intervene when possible.

[1] Following the release of AJR's single "Weak", Obama listened to the song via Spotify,[2] which led to his administration asking the band to help support the campaign.

[3] The band accepted, describing the movement's goals as "an important topic to us because most of our fans are in that college-age demographic, and it presents a real problem on college campuses" and expressed happiness with using AJR's popularity as a platform for it.

[6] AJR performed "It's On Us" alongside their song "Turning Out" from the band's second studio album, The Click, and a cover of "Can't Help Falling in Love" by Elvis Presley at the White House for the final It's On Us summit on January 5, 2017.