It explored the possibilities of various weather and other natural phenomena severely damaging or destroying America's cities.

This included: a Category 3 hurricane hitting New York City, an F4 tornado destroying Washington, D.C., dormant volcano Mount Rainier re-activating and destroying towns in the surrounding valleys, a tsunami flooding the Pacific Northwest coast, an intraplate earthquake impacting Memphis, Tennessee, wildfires spreading into the heart of San Diego, a huge earthquake leveling San Francisco, a flash flood in Boulder, Colorado, and a flood in Sacramento.

More recent episodes included an earthquake in Las Vegas, an F5 tornado ripping its way through Chicago and Dallas, and more.

[citation needed] Because Hurricane Sandy was only a category 1 and not a 3 when New York was hit, the first episode hadn't technically come true, although Sandy was the closest call since the series ended In 2024, the Tampa Bay Area was hit by Hurricane Milton, fulfilling the show’s prediction of a major hurricane impacting the Tampa Bay Area.

As of July 2013, two episodes aired Fridays at 4–5 pm, but as of October 2013, it is no longer on TWC's schedule.