The San Giorgio class of the Italian Navy, also known as the Santi class (since the three units that compose it have the names of three saints), consists of three amphibious warships of the landing platform dock (LPD) type: the San Giorgio, the San Marco and lastly, with a slightly different design, the San Giusto, specialized in landing operations that replaced the Grado and Caorle which were disarmed at the end of the 1980s.

San Marco was laid down on 26 March 1985 and launched on 10 October 1987 by Fincantieri at Riva Trigoso.

Starting from December 1992 the San Giorgio, San Marco and the men of the San Marco Battalion took part in Somalia in the Ibis I and Ibis II missions with the 24th Naval Group together with Vittorio Veneto, Vesuvius and Grecale and with the 25th Naval Group together with the Giuseppe Garibaldi, the Stromboli and Scirocco.

food intended for the non-combatant civilian population made available by the Ministry of Foreign Affairs, the Civil Protection, the Italian Red Cross and the United Nations World Food Program.

On 16 June 2016, San Marco, Bersagliere, Cigala Fulgosi, Andrea Doria, Carlo Margottini, Etna and Stromboli participated in the Flotta Verde exercise as part of the Great Green Fleet initiative.