It was centered around Yoshida jin'ya, located in what is now part of the city of Uwajima, Ehime, and was ruled throughout its history by a cadet branch of the tozama daimyō Date clan.

During his tenure, Munezumi fell ill and was attended to by a wandering physician from Tosa Domain named Yamada Chūzaemon.

He was well-versed in literary and military arts and was awarded a fief of 100 koku and persuaded to stay in Yoshida as Munezumi's advisor.

Yamada persuaded Munezumi that he should reduce the domain's expenditures by demoting senior retainers who had held their posts for multi-generations and who were receiving high levels of compensation.

This understandably made many retainers upset, leading to an armed uprising known as the "Yamada Disturbance"and an appeal directly to Sendai Domain.

During the Bakumatsu period, Iyo-Yoshida was a supporter of the shogunate, but was restrained from any active participation in the Boshin War by Uwajima Domain, and thus escaped punishment by the new Meiji government.