Izon’s size-exclusion chromatography columns and related solutions are also used by diagnostics companies focused on developing extracellular vesicle biomarkers.

Presently, Izon Science develops and manufactures tools for nanoparticle characterization and separation, catering to academic researchers and diagnostics companies working with extracellular vesicles, as well as those involved in nanomedicine, viruses, and virus-like particles.

Tunable resistive pulse sensing (TRPS) is a single-particle analytical technique used to measure the size, concentration, and charge of nano and micro-sized particles by detecting a change in ionic current.

The passage of an individual particle through a charged nanopore creates a transient change in resistance and subsequent decrease in the background current, known as a blockade event.

Size exclusion chromatography-based qEV columns contain porous polysaccharide resins, which enable extracellular vesicles to be isolated in preparation for a range of downstream analytical methods.

The Automatic Fraction Collector (AFC) is a programmable, automation technology designed to enhance the reproducibility and scalability of sample collection from qEV columns.

It has an in-built rotational carousel for holding collection tubes, and precisely measures the volume of each fraction by weight as the sample elutes from the column.

The Exoid is the most recent tunable resistive pulse sensing instrument developed by Izon Science and incorporates automated systems to avoid the extensive manual tuning associated with the qNano.

Unlike the qNano, the Exoid has built-in semi-automated components for controlling pressure and nanopore stretch, and an enhanced voltage clamp amplifier.