He was the founder of the Zawadzki Press and was the official publisher of the Imperial University of Vilnius.
He published 851 books, mostly in Polish, but also in Latin, Greek, Hebrew and Lithuanian.
In 1810, Zawadzki with J. Węcki opened a branch of his printing house in Warsaw.
He published Historia literatury polskiej of Feliks Bentkowski (1814), Poezje vol.
1–2 of Adam Mickiewicz (1822–1823), works of Joachim Lelewel, Jan Śniadecki and Jędrzej Śniadecki, Słownik łacińsko-polski of Florjan Bobrowski (1822), calendars, music sheets, magazines, textbooks.