It intersects with Lawton Avenue just past the University of Makati campus, which connects it to Bonifacio Global City nearby.

The road gradually pulls away from the river, continuing on a straight path to Chino Roces Avenue and A.P.

The section from Makati Avenue then carries one-way westbound traffic, especially during daytime and rush hours up to Pasong Tirad.

[2][3][4] The avenue then curves northwest past Pasong Tirad before coming to its western terminus at Zobel Roxas and Delpan Streets at the city's border with Manila, continuing as Tejeron Street.

[6][7] Its segment from Malapad-na-bato (now East Rembo, the present-day location of Napindan Hydraulic Control System) westwards was also part of Route 21 or Highway 21 that linked Manila to Calamba, Laguna by circumscribing Laguna de Bay through Rizal, especially during the American colonial era.