Mann is also a magnet school for math, science, and technology, allowing students to receive honorary distinction in one of the three areas when they graduate.

[3] J. L. Mann High School opened on July 1, 1965, in the East Parkins Mill Road area of Greenville.

On January 5, 2008, students and faculty moved into a new building, which replaced the original high school constructed in 1964.

Mann sports programs include cross country, track and field, swimming, softball, baseball, tennis, wrestling, soccer, football, basketball, golf, lacrosse, and volleyball.

[7] Under adviser Phillip Caston from 2006 to 2013, Mannuscript received the Palmetto Award six times for best in its class from SCSPA as well as six All-State ratings.