John Louis Comiskey (August 12, 1885 – July 18, 1939) was an American businessman and the owner of the Chicago White Sox of the American League from 1931 to 1939.

He was born on August 12, 1885, son of Charles Comiskey.

He started work for the White Sox in 1910.

Comiskey died of heart disease at the age of 53 on July 18, 1939.

This biographical article relating to an American baseball executive is a stub.