Jacob van der Hoeden (Hebrew: יעקב ואן דר הודן, 27 July 1891 in Utrecht – 1 February 1968) was a Dutch-born Israeli veterinary research scientist.

Jacob (Jaap) Van der Hoeden was born into a Jewish family in the Netherlands in 1891.

Van der Hoeden, together with his four children, survived the Holocaust thanks to the help of Dutch Christians who hid the family in various places.

Van der Hoeden served from 1924 to 1929 as a senior researcher at the Dutch national public health institute and a professor of veterinary medicine at Utrecht University.

In 1929, he was appointed to head the University's hospital laboratories and, in 1932, was elected to the Dutch Society for Natural Sciences.