[2] In 2006, he won the Italian Formula Renault Winter Series,[3] before finishing as runner-up to Mika Mäki in the main championship the following year.

[4] He moved up to the British Formula Three Championship for 2008, driving for the Carlin Motorsport alongside teammates Brendon Hartley, Oliver Turvey and Sam Abay.

[7] At the time of his move to Formula One mid-season, he was eighth in the championship, with one podium finish, and was the second-highest rookie driver in the standings behind Turvey.

[13] Less than two weeks later, race driver Sébastien Bourdais left the Toro Rosso team after the 2009 German Grand Prix and Alguersuari was immediately expected to be his successor, despite the lack of an official confirmation.

[16] He became the youngest ever Formula One driver at the age of 19 years and 125 days, breaking the record previously held by Mike Thackwell.

[18] Toro Rosso retained Alguersuari for the 2010 season,[19] starting with a career-best finishes of thirteenth in Bahrain and eleventh in Australia including 22 laps battling with the 7 time world champion Michael Schumacher.

Toro Rosso team principal Franz Tost praised Alguersuari's performance, saying the Spaniard "drove a fantastic race".

In May, Alguersuari visited the Dominican Republic with his Red Bull team and became one of the first drivers to ever drive a Formula 1 vehicle on the beaches there.

[22] After finishing the first two races outside the points, Alguersuari qualified inside the top ten for the first time in Formula One, with a seventh place grid start in China.

He qualified a career best 6th at the Belgian Grand Prix before being forced to retire during the race after a first corner collision with Bruno Senna.

Following the last race of the season in Brazil, Alguersuari won the Desafio Internacional das Estrelas karting event, organised by Felipe Massa.

[25] On 14 December 2011, Toro Rosso announced that Ricciardo and Jean-Éric Vergne would be the team's drivers in 2012, replacing Alguersuari and Buemi.

Alguersuari had to miss the final two rounds of the season due to minor health issues which caused him to faint at the end of the 2015 Moscow ePrix and was replaced by Fabio Leimer.

[37] He also returned to participate in the Spanish karting championship[38][39][40] In addition to driving racing cars, Alguersuari has his own recording studio in Barcelona,[41] and is well known in Spain as a DJ, under the stage name Squire (in reference to his second surname Escudero).