[3][4] In 2009, Ortiz auditioned and was cast on the second season of VH1's reality show Scream Queens,[5] where she and nine other aspiring actresses competed in challenges based on acting for the opportunity to win the prize of a role in Saw 3D.

[6] In 2012, Ortiz was in a photo used in the Modern Family episode Yard Sale where she was beauty pageant contestant Miss Galapa.

[7] In 2013, Ortiz landed the role as a series regular in The After, produced by The X-Files creator, Chris Carter.

[8] The pilot, which began airing via Amazon Video in February 2014,[9] received positive feedback and was ordered to series.

In 2017, Ortiz was cast in a leading role on the spin-off to ABC's longest-running drama series Grey's Anatomy, titled Station 19.