[1] In 2011, Mills registered 26 tackles, one interception, and six pass breakups, helping the DeSoto Eagles to a 10–2 record and a second-round UIL 5A Division 1 playoff appearance, where they lost 41–31 to Dallas Skyline.

[2] Mills was rated by Rivals.com as a three-star recruit and committed to Louisiana State University (LSU) to play college football under head coach Les Miles.

Although he was thought as a top draft pick during his junior year, his stock fell when he suffered a fractured fibula and tore ligaments in his ankle in August 2015.

[9] All 32 NFL teams were represented by coaches and scouts to watch Mills, Deion Jones, Vadal Alexander, Lamar Louis, Jerald Hawkins, Quentin Thomas, Reid Ferguson, and five others perform drills at LSU's pro day.

[15] He competed with Eric Rowe, Ron Brooks, Denzel Rice, and Aaron Grymes for a backup cornerback job throughout training camp.

Head coach Doug Pederson named Mills the fourth cornerback on the Eagles' depth chart to begin the regular season, behind Nolan Carroll, Leodis McKelvin, and Ron Brooks.

[16] On September 11, 2016, Mills made his professional regular season debut in the Eagles' season-opener against the Cleveland Browns and he recorded two solo tackles in the 29–10 victory.

[17] The following week, Mills collected a season-high six solo tackles and defended a pass during a 29–14 win over the Chicago Bears.

On October 16, 2016, he earned his first career start and recorded a season-high seven combined tackles and two pass deflections during a 20–27 loss to the Washington Redskins.

[18] He competed with Patrick Robinson, Ron Brooks, Ronald Darby, Aaron Grymes, and Rasul Douglas for one of the vacant starting cornerback jobs left by the departures of Nolan Carroll and Leodis McKelvin.

Mills was named a starting cornerback along with Ronald Darby and Patrick Robinson to begin the regular season.

[20] In a Week 3 matchup against the New York Giants, Mills recorded a season-high 12 combined tackles and deflected two passes in a 27–24 victory.

[25] Mills was placed on the reserve/physically unable to perform (PUP) list on August 31, 2019, due to the foot injury suffered last season.

[47] On June 10, 2014, Baton Rouge police arrested Mills on a suspicion of second degree battery against a woman that had occurred on May 4, 2014.

[51] On April 12, 2019, Mills was arrested and charged with disorderly affray for an altercation with Devin Robinson of the Washington Wizards, outside a DC nightclub.