Sir James Cambell or Campbell (c. 1570 – 5 January 1642) was an English merchant who was Lord Mayor of London in 1630.
Like his father, Campbell became a City merchant and joined the Worshipful Company of Ironmongers.
According to his will, he left almost £50,000 to a large number of legacies to relatives, friends, London hospitals, a free school at Barking in Essex, the Ironmongers' Company, and for the ransom of poor captives from Turkish slavery.
His widow, Rachel (Lady Campbell), survived until January 1657, but he left no children.
His brother, Sir Robert Campbell, was also a City Alderman and served as Master Ironmonger in 1631.