James Clow (26 May 1790 – 15 March 1861) was a Presbyterian minister, in the area which now consists of the outer-eastern suburbs of Melbourne, Australia.

[1] Chow arrived in Bombay on 8 November 1815, and on 15 December attended a meeting called by the government to select a site and consider plans for a church.

He was back in India on 10 March 1819 and opened St Andrew's church on 25 April following, Clow was frequently away for long periods on sick leave and retired from the service on 10 October 1833.

Tirhartruan was located on the north side of Wellington Road, just east of Dandenong Creek, and was the subject of an archaeological dig in the 1970s.

He preached and laboured among the colonists, taking no salary, and occupying no stated pastorate, and was the inspirer and founder of the Scots Church erected in Collins Street.