He was the son of Robert Crichton of Eliok, Lord Advocate of Scotland, and Elizabeth Stewart, from whose line James could claim Royal descent.
[1] One of the most gifted individuals of the 16th century, Crichton was educated at St Andrews University between the ages of ten and fourteen, during which time he completed requirements for both his bachelor's and master's degrees.
[1] By the age of twenty, he was not only fluent in, but could discourse in (both prose and verse) no fewer than twelve languages, as well as being an accomplished horseman, fencer, singer, musician, orator, and debater.
Thereafter he spent two years as a soldier in the French army before travelling to Italy in 1579, winning acclaim in Genoa, Venice, and Padua by repeating his exploit of challenging Italian scholars to intellectual discourse and debate.
In Venice in 1580, Crichton befriended the printer Aldus Manutius, who introduced him to the Venetian intellectual community, where the young Scot made an enormous impression on humanist scholars.
Much of Crichton's posthumous reputation comes from a romantic 1652 account of his life written by Sir Thomas Urquhart (1611–1660), contained within an unclassifiable work (The Jewel) that is characterized by exaggeration and hyperbole.