[5] Denton graduated from Goodlettsville High School, and attended the University of Tennessee, where he was a member of the Sigma Alpha Epsilon fraternity.

He added a steady string of roles and accolades to his quickly growing list of achievements, including one of the leads in the world premiere of Flesh and Blood, performing in and composing the music for The Night Hank Williams Died, and his portrayal of Kentucky preacher "C.C.

After moving to Los Angeles, Denton continued to perform on stage, usually during hiatus from whichever TV series to which he was attached at the time.

In 2003, he portrayed the lead role of Special Agent John Kilmer in the short-lived crime thriller series Threat Matrix.

[7] The show was well received by viewers and critics and it won multiple Primetime Emmy, Golden Globe and Screen Actors Guild Awards.

[14] Denton portrays Dr. Sam Radford, a starring role on Hallmark Channel's fantasy comedy-drama television series Good Witch.

[16] The New York Times called the series "a gentle, sentimental prime-time fable set in an idealized Middle American small city (not an angsty suburb), is the show you find your parents or grandparents watching when you come home for a visit.

"[17] In 2019, the show was one of the network's most popular original series, and the Good Witch closed season five in first place among household ratings on Sundays.

[19] In 2018, he made a guest appearance as Navy Captain Deckard on CBS' television series NCIS: New Orleans, in the episode "Checkmate, Part 2".

[5][27] Denton has supported the Angel Foundation, a nonprofit organization based in Minnesota, serving adults with cancer and their families.