James Gerald Hirsch (October 31, 1922 – May 25, 1987) was an American physician and biomedical researcher who specialized in immunology.

Hirsh graduated from Columbia University's College of Physicians and Surgeons in 1946 with an M.D.

[4] [5] In 1957 his research showed that a prolonged rest is not needed for treatment of the tuberculosis, and resulted in international changes to how tuberculosis patients are treated by allowing local hospitals rather than sanatoriums to take care of the sick.

[1] The New York Times called Hirsch "a leader in blood research".

[1] The National Academies Press called him "a pivotal figure in leukocyte biology".