James Gyakye Quayson (born 9 October 1952) is a Ghanaian politician who is currently serving as the member of Parliament (MP) for Assin North.

[14][15][16] The Supreme Court set 13 June 2022 for the trial against Quayson after postponing his application review for restraining him to hold himself as MP and preventing him to attend Parliament to conduct business on behalf of the people of Assin North constituency.

[17][18] In a unanimous decision by The Supreme Court of Ghana consisting of Justices Jones Dotse, Nene Amegatcher, Mariama Owusu, Gertrude Torkonoo, Henrietta Mensah-Bonsu, Emmanuel Kulendi and Barbara Ackah Ayensu, presiding Judge Justice Jones Dotse on 17 May 2023 ruled that the Electoral Commission of Ghana acted unconstitutionally by accepting the nomination of Mr. Quayson without proof of citizenship renunciation before contesting the 2020 parliamentary elections.

[26][needs update] Mr. Quayson, in a statement on 1 June 2023, officially declared his intention to contest in the Assin North constituency by-election with support from his party, the National Democratic Congress.

James Gyakye Quayson, after emerging victorious in the by-election was sworn in for the second time as the Member of Parliament for Assin North on Tuesday, 27 June 2023.