James Humphrey (October 9, 1811 – June 16, 1866) was a U.S. Representative from New York.

He moved to Louisville, Kentucky, in 1837 and one year later to Brooklyn, New York.

Humphrey was elected to the Thirty-ninth Congress and served from March 4, 1865, until his death in Brooklyn, New York, June 16, 1866.

He served as chairman of the Committee on Expenditures in the Department of the Navy (Thirty-ninth Congress).

This article incorporates public domain material from the Biographical Directory of the United States Congress