The James Mitchell House is a historic home located at Indiana, Indiana County, Pennsylvania.

The front section was built about 1850, and is a 2+1⁄2-story brick building with a gable roof in a vernacular Federal-style.

It has a 2+1⁄2-story frame rear wing, making for an L-shaped building.

[2] It was added to the National Register of Historic Places in 1978.

This article about a property in Pennsylvania on the National Register of Historic Places is a stub.