James Sullivan Wiley (January 22, 1808 – December 21, 1891) was a U.S. Representative from Maine.
He moved to Dover, Maine, and was an instructor at the Foxcroft Academy.
He studied law and was admitted to the Piscataquis County bar in 1839 and commenced practice in Dover.
He moved to Fryeburg, Maine, in 1889 and continued the practice of law until his death in that town on December 21, 1891.
Wiley's 1849 home in Dover-Foxcroft is listed on the National Register of Historic Places.