Jane Chambers McKinney Graydon (July 16, 1802 – March 30, 1891)[1] was an abolitionist who served as a nurse during the American Civil War.

In collaboration with Catharine Merrill, she organized a charitable society in 1867 that founded the Indianapolis Home for Friendless Women, the predecessor to the Indianapolis Retirement Home.

She married Alexander Graydon, an iron manufacturer, in 1822 and they moved to Indianapolis, Indiana, in 1843.

[2] During the American Civil War, she served as a nurse in Tennessee.

[4] With Catharine Merrill, who also served as a nurse during the war, Jane McKinney Graydon organized the charitable group that established the Indianapolis Home for Friendless Women in 1867.