Jane Middleton (December 24, 1818 — July 30, 1885) was an English-born American philanthropist, one of the founders and superintendent of the first Home for Aged and Infirm Deaf-Mutes in New York City, located at 220 East 13th Street, from its inception in 1872 until her death in 1885.
Her father was a druggist, and the family lived in Manchester, England prior to coming to the United States in 1839.
[5][6] After years of running boarding houses for Christian young women and men, Jane Middleton opened a home for aged deaf-mutes, the first such establishment in the country.
[7] In 1872 the transition was complete and Jane became the Home's superintendent, and would continue this work until her passing in 1885, apparently without pay.
[10] Middleton arranged for several local private physicians, along with doctors at the New York Eye and Ear Infirmary also located at 2nd Avenue and 13th Street, to donate their time and services to the Home.