National Route 210 is a national highway of Japan connecting Kurume and Ōita in Japan, with a total length of 136.2 km (84.63 mi).

The highway passes through the cities of Kurume and Ukiha in Fukuoka Prefecture, and also Hita, Kusu, Yufuin and Yufu in Ōita Prefecture, before ending in Ōita.

It runs roughly parallel to Kyūdai Main Line, a JR Kyushu railway line between Kurume and Ōita, and Ōita Expressway, which the route directly connects to via Yufuin IC [ja] in Yufuin.

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