Henderson attended Delaware Valley High School in Dingmans Ferry, Pennsylvania, where he was a two-way player in football.
[2] In week 12 of the 2021 season, Henderson forced a fumble that helped Old Dominion clinch their 24-17 win over Middle Tennessee.
[8] Henderson finished his breakout 2022 season notching 186 tackles with ten being for a loss, a sack, and three pass deflections.
[11] Henderson was also named first-team all Sun-Belt,[12] and a second-team All-American, being the first Old Dominion player to do so at the FBS rank.
[13] Ahead of the 2023 season, Henderson was named to the Bronko Nagurski Trophy watchlist,[14] as well as the preseason Sun Belt defensive player of the year.