His most notable acting roles came through Urumi (2011) and as Ajith Kumar's friend in Gautham Vasudev Menon's Yennai Arindhaal (2015).
[2][3] Radhakrishnan made his directorial debut through the bilingual film Lens starring Anand Sami and Vinutha Lal in lead roles alongside himself.
The plot for the film emerged over drinks with Radhakrishnan's friend Suresh, who eventually played the protagonist.
Radhakrishnan revealed "with no script in hand, everyone responded spontaneously to the developing plot from the depth of their own experiences".
His next release will be Kadhal Enbadhu Podhu Udamai, a LGBT-romantic drama film starring Lijomol Jose and Anusha in the lead roles.