Jean-Marie Ducharme (French pronunciation: [ʒɑ̃ maʁi dyʃaʁm]; July 19, 1723 – July 20, 1807) was a fur trader and political figure in New France, British Quebec, and Lower Canada.
He was born in Lachine, New France in 1723, the son of a farmer there who also was involved in the fur trade.
During 1779–80, he helped lead a British expedition against the Spanish at St. Louis, in the Anglo-Spanish War.
After he retired from the fur trade, Ducharme represented Montreal County in the Legislative Assembly of Lower Canada from 1796 to 1800.
His son Dominique also entered the fur trade and later served with distinction during the War of 1812.