From there she left to Melbourne, Victoria after having successfully completed her nursing training at St. Andrew's War Memorial Hospital in Brisbane[5] (for which, in 1966, she won a study scholarship from then Queensland Peanut Marketing Board and Trans Australian Airlines).

Little is known for her extensive community work in the health, as a consultant on Cultural Awareness across the corporate sector, advocacy against deaths in custody and involvement within politics in relation to Indigenous Affairs.

[6] Little is a Life Member of the now closed Alcohol and Other Drugs Council of Australia (ADCA) Australia's peak body in alcohol and substance abuse and misuse research, and in 2012 she was elected by her peers to be the first Aboriginal woman to sit on the Board of Directors.

[8] Little currently sits on a number of community led committees who advocate against the use of excessive force from Police Officers on prison or watch-house inmates.

In 2011 Little, also a writer and poet,[14] was selected as one of Queensland's State Finalists for the National Poetry Slam.