Jean Littlejohn OBE CBE (3 April 1899 – 27 November 1990) was an Australian surgeon, early practitioner of the developing field of otorhinolaryngology, and pioneer of deafness research.

[1][5] Littlejohn was drawn to the new field of ear, nose, and throat surgery (otorhinolaryngology), which was developing rapidly at this time along with technological advances that enabled more precise surgical investigation and treatment of these areas.

[1][5] During World War II Littlejohn served as an ENT surgeon to the armed forces.

In 1947 she was appointed clinical dean of the Eye and Ear Hospital and became the first woman elected to the University of Melbourne faculty of medicine.

[5] In 1978 the University of Melbourne's Department of Otolaryngology awarded the first biennial Jean Littlejohn Otorhinolaryngology research prize.