[1] After the American Revolution, the Prendergast family, consisting of the children, grandchildren, and servants, traveled to Wheeling, West Virginia and then to Louisville, Kentucky, before they arrived in Memphis, Tennessee.

[2] The Prendergast family moved to Chautauqua County, New York, and Jediah settled in Mayville in 1811.

Prendergast was married to Penelope Chase, a native of Rhode Island.

[3][1] In 1819, he was elected President of the Chautauqua County Medical Society to serve for a year.

[1] Jediah Prendergast's wife Penelope died on February 1, 1845, while visiting family in Canada.