Jeffrey is an unincorporated community located near Peter/s Creek on Bethlehem Church Road, approximately eight miles (13 km) northwest of Tompkinsville, Monroe County, Kentucky, United States.

A post office was first established here, March 10, 1903, in the home of postmaster and namesake, Payton J. Jeffrey/s (1865–1926), and his wife, Ella (Arterburn) Jeffrey/s, which was later moved to their general store.

Payton Jeffrey/s also operated a grist mill located across from his store on Peter/s Creek, succeeded as miller by his son-in-law, George Simmons.

[4][5] Argil Black, Joe Bowman, William Joseph Burks, Finley Quinn, Leslie Samson, John Bedford Smith, and J. T. Turner were also merchants in this community.

William T. Whitehead briefly operated a steam-powered sawmill on Kate Miller Branch of Peter/s Creek nearby.